Expanded cardiac rehabilitation in socially vulnerable patients with myocardial infarction: A 10-year follow-up study focusing on mortality and non-fatal events

Kathrine Hald, Kirsten Meldgaard Nielsen, Claus Vinther Nielsen, Lucette Meillier, Finn Breinholt Larsen, Bo Christensen, Mogens Lytken Larsen
Cardiac rehabilitation (CR) has been shown to reduce cardiovascular risk. A research project performed at a university hospital in Denmark, offered an expanded CR intervention to socially vulnerable patients. One-year follow-up showed significant improvements concerning medicine compliance, lipid profile, blood pressure and body mass index, when compared to socially vulnerable patients receiving standard CR. The aim of the study was to perform a long-term follow-up on the socially differentiated CR intervention and examine the impact of the intervention on all-cause mortality, cardiovascular mortality, non-fatal recurrent events and major cardiac events (MACE) 10 years after.

Prospective cohort study.

The cardiac ward at a university hospital in Denmark from 2000 to 2004.

379 patients < 70 years admitted with first episode myocardial infarction (MI). The patients were defined as socially vulnerable or non-socially vulnerable according to their educational level and their social network. A complete follow-up was achieved.

A socially differentiated CR intervention. The intervention consisted of standard CR and additionally a longer phase II course, more consultations, telephone follow-up and a better handover to phase III CR in the municipal sector, in general practice and in the patient association.

Main outcome measures:
All-cause mortality, cardiovascular mortality, non-fatal recurrent events and MACE.

There was no significant difference in all-cause mortality (OR:1.29, 95%-CI 0.58;2,89), cardiovascular mortality (OR:0.80, 95%-CI 0.31;2.09), non-fatal recurrent events (OR:1.62, 95%-CI 0.67;3.92) or MACE (OR:1.31, 95%-CI 0.53;2.42) measured at 10-year follow-up when comparing the expanded CR intervention to standard CR.

Despite the significant results of the socially differentiated CR intervention at one-year follow-up, no long-term effects were seen regarding the main outcome measures at 10-year follow-up. Future research should focus on why it is not possible to lower the mortality and morbidity significantly among socially vulnerable patients admitted with first episode MI.

Link til full text article: https://www.ncbi.nlm.nih.gov/pubmed/29362268

Udgivelsesform Videnskabelige artikler
År 2018
Udgiver BMJ Open


Finn Breinholt Larsen Kathrine Hald ; Claus Vinther Nielsen ; Lucette Kirsten Meillier